ProTools is jaw-droppingly awesome.  Audacity is minimal but sometimes adequate.  Ardour is just frustrating.  I wish Jokosher the best of luck, but right now it’s a toy.

I just read about REAPER today, and downloaded it.  All 3MB of it.  It’s not ProTools, but it’s pretty impressive (and doesn’t require buying an M-box).  I don’t have any projects right now, but next time I do, I’m going to give it a serious shot.

Windows only, alas.